PIE *nas「鼻」から、おそらく擬音語から、語源はnasal「鼻孔」と同じ。
Kiv, It could bee no other then his owne manne, that had thrust his nose so farre out of ioynte. ["Barnabe Riche His Farewell to Military Profession," 1581]Pay through the nose (1670s) seems to suggest "bleed." Many extended meanings are from the horse-racing sense of "length of a horse's nose," as a measure of distance between two finishers (1908). To turn up one's nose "show disdain" is from 1818 (earlier hold up one's nose, 1570s); similar notion in look down one's nose (1921). To say something is under (one's) nose "in plain view" is from 1540s.