Old English wieutan "outside of, from outside," literally "against the outside" (opposite of within), see with + out (adv.). As a word expressing lack or want of something (opposite of with), attested from c. 1200. In use by late 14c. as a conjunction, short for without that.
例文
1. When life gets hard and you want to give up,remember that life is full of ups and downs,and without the downs,the ups would mean nothing.